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#longevity

2 posts2 participants0 posts today
Public
Lazarou Monkey Terror 🚀💙🌈

You and I all deserve a few extra decades for all the shit Capitalism has put us through as it dies.

"But bad people will have longevity as well!" then do something about the bad people rather than wait for them to die. ffs...

sciencealert.com/scientists-co

ScienceAlert · Scientists Confirm Anti-Aging Drug Appears to Prolong Life in AnimalsFor centuries, humans have searched for ways to extend life.
#Longevity#AntiAging
Public
Roman ALAN

The internet is full of little snippets of 'gosh' knowledge:

"The observation of individuals attaining remarkable ages, and their concentration into geographic sub-regions or ‘blue zones’, has generated considerable scientific interest. Proposed drivers of remarkable longevity include high vegetable intake, strong social connections, and genetic markers.

…

These [extreme old-age] data reveal that remarkable age attainment is predicted by indicators of error and fraud, including illiteracy, poverty, high crime rates, short average lifespans, and the absence of birth certificates."

from "Supercentenarian and remarkable age records exhibit patterns indicative of clerical errors and pension fraud",
Saul Justin Newman bioRxiv 704080; doi: doi.org/10.1101/704080

This was awarded an Ig Noble Prize (for scientific research that makes you laugh, then think) in 2024.

bioRxiv · Supercentenarian and remarkable age records exhibit patterns indicative of clerical errors and pension fraudThe observation of individuals attaining remarkable ages, and their concentration into geographic sub-regions or ‘blue zones’, has generated considerable scientific interest. Proposed drivers of remarkable longevity include high vegetable intake, strong social connections, and genetic markers. Here, we reveal new predictors of remarkable longevity and ‘supercentenarian’ status. In the United States, supercentenarian status is predicted by the absence of vital registration. The state-specific introduction of birth certificates is associated with a 69-82% fall in the number of supercentenarian records. In Italy, England, and France, which have more uniform vital registration, remarkable longevity is instead predicted by poverty, low per capita incomes, shorter life expectancy, higher crime rates, worse health, higher deprivation, fewer 90+ year olds, and residence in remote, overseas, and colonial territories. In England and France, higher old-age poverty rates alone predict more than half of the regional variation in attaining a remarkable age. Only 18% of ‘exhaustively’ validated supercentenarians have a birth certificate, falling to zero percent in the USA, and supercentenarian birthdates are concentrated on days divisible by five: a pattern indicative of widespread fraud and error. Finally, the designated ‘blue zones’ of Sardinia, Okinawa, and Ikaria corresponded to regions with low incomes, low literacy, high crime rate and short life expectancy relative to their national average. As such, relative poverty and short lifespan constitute unexpected predictors of centenarian and supercentenarian status and support a primary role of fraud and error in generating remarkable human age records. ### Competing Interest Statement The authors have declared no competing interest.
#IgNobelPrize#Longevity#Supercentenarian
Public
N-gated Hacker News

🚀 Wow, a double negative title that makes "Life Extension" sound like a rebellious teenage phase! 🙄 Apparently, fighting for #longevity is as contentious as preferring pineapple on pizza—because who needs more time to argue? 🍍⌛
alexkesin.com/p/contra-fukuyam #LifeExtension #DoubleNegative #Debate #PineappleOnPizza #RebelliousPhase #HackerNews #ngated

Alex Kesin's Pharmacopoeia · Against "Against Life Extension"By Alex Kesin
Public
Thomas Dugaro

I wish everything was as solid and long-lasting as my #stereo.
It consists of a record player from 1992 (#Technics SL-MK #1210), a CD player and a tape recorder from 1995, and a tuner and an amplifier from 1997 (all by #Yamaha).

They have never faltered or failed me. They just work and sound like they did on day one.

My speakers are from 1976 and, for nostalgic reasons, I have never replaced them – although I guess it would make a difference in this case.

A turntable and an amplifier on top of a brown shelf. Above them a few 7" singles and CDs
#longevity#sustainability#music
Public
freespirit利努克斯 :debian:

Hallo zusammen!
In diesem Monat planen wir einen Podcast zum Thema Open Source und ich würde gerne ein paar Fragen an euch richten. Euer Feedback wäre sehr wertvoll für mich, um verschiedene Perspektiven zu sammeln.
Vielen Dank im Voraus!

Hello everyone! This month, we are planning a podcast on the topic of Open Source, and I would like to ask you a few questions. Your feedback would be very valuable to me in gathering different perspectives.
Thank you in advance!

Allgemeines Verständnis von Open Source:

Was bedeutet für euch „Open Source“ und wie hat es eure Sichtweise auf Software verändert?

General understanding of open source:

What does “open source” mean for you, and how has it changed your view of software?

#OpenSource #Gemeinschaft #Unterstützung #Spenden #Nachhaltigkeit #Innovation #Vielfalt #Entwickler #Freiwillige #Technologie #Zusammenarbeit #Engagement #Zugang
#Inklusivität #Ressourcen #Wissensaustausch #Projekte #Langfristigkeit #Verbesserung
#Zusammenarbeit
#Linux #Freiheit #Foss #KeinMicrosoft #KeinGoogle

#Community#Support#Donations
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freespirit利努克斯 :debian:

Dear Community,

We live in a time when open-source software plays a vital role in technology. The innovative power and diversity that arise from open-source projects are indispensable for many of us. However, these valuable initiatives need our support to continue existing and thriving. Many of these projects are run by dedicated developers and volunteers who tirelessly work to improve and develop their software.
Unfortunately, this passion is often not sufficiently financially supported. Open-source software allows us to access a wide range of tools and resources that not only facilitate our work but also promote collaboration and knowledge sharing.
By supporting these projects, we contribute to an open and inclusive technology world where everyone has access to critical technologies.
To ensure the longevity and sustainability of these projects, it is crucial that we all do our part. Even the smallest donation can make a big difference. Consider whether you have the opportunity to support your favorite projects. Perhaps you also have the ability to actively contribute to development or provide feedback to further improve these projects.
Let’s work together to ensure that the open-source community continues to flourish! Your support can help these projects provide innovation, diversity, and free software for everyone in the future. By pooling our resources and commitment, we can build a strong community that values and promotes the benefits of open collaboration.
Thank you for your commitment!

#OpenSource#Community#Support
Public
Peter Spork

Revolutionärer Barcode für Blutzellen

Forschenden aus Spanien und Deutschland gelang jetzt ein großer Durchbruch. Mit "EPI-Clone" können sie das epigenetisch aktive Muster der DNA-Methylierung tausender Blutzellen aus einer Probe so geschickt analysieren, dass jede Zelle individuell erfasst wird.

Diese Einzelzell-Epigenomik liefert regelrechte Barcodes der Zelle. Erste Erkenntnis: Im Alter ändert sich das Blutsystem deutlich. Immer weniger Stammzell-Linien müssen das gesamte Blutsystem erneuern. Das Risiko für chronische Entzündungen und damit Alterskrankheiten steigt.

Die Methode soll jetzt den Weg zu einer hochpräzisen Altersmedizin begleiten und den Erfolg zukünftiger Medizin messbar machen.

Die Nature-Studie ist erst seit wenigen Stunden online. Ich berichte schon jetzt auf newsletter-epigenetik.de und am Freitag in der nächsten Ausgabe der .
@riffreporter

Foto: Blutstammzellen der Maus in 20-facher Vergrößerung. (Bildrechte: Julia Rühle/Centro de Regulación Genómica)

Blutstammzellen der Maus in 20-facher Vergrößerung sehen aus wie viele graue Kügelchen nebeneinander.
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