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UK<a href="https://www.europesays.com/uk/10705/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.europesays.com/uk/10705/</a> Serotonin Helps Your Brain Predict Future Rewards <a href="https://pubeurope.com/tags/BrainResearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BrainResearch</a> <a href="https://pubeurope.com/tags/Health" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Health</a> <a href="https://pubeurope.com/tags/neurobiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neurobiology</a> <a href="https://pubeurope.com/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neuroscience</a> <a href="https://pubeurope.com/tags/RewardSystem" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#RewardSystem</a> <a href="https://pubeurope.com/tags/serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#serotonin</a> <a href="https://pubeurope.com/tags/UK" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#UK</a> <a href="https://pubeurope.com/tags/UnitedKingdom" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#UnitedKingdom</a> <a href="https://pubeurope.com/tags/UniversityOfOttawa" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#UniversityOfOttawa</a>

UK<a href="https://www.europesays.com/uk/403/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.europesays.com/uk/403/</a> Intermittent Fasting Boosts Male Libido by Lowering Serotonin <a href="https://pubeurope.com/tags/BrainResearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BrainResearch</a> <a href="https://pubeurope.com/tags/diet" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#diet</a> <a href="https://pubeurope.com/tags/DZNE" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#DZNE</a> <a href="https://pubeurope.com/tags/Health" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Health</a> <a href="https://pubeurope.com/tags/IntermittentFasting" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#IntermittentFasting</a> <a href="https://pubeurope.com/tags/neurobiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neurobiology</a> <a href="https://pubeurope.com/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neuroscience</a> <a href="https://pubeurope.com/tags/reproduction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#reproduction</a> <a href="https://pubeurope.com/tags/serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#serotonin</a> <a href="https://pubeurope.com/tags/SexDrive" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SexDrive</a> <a href="https://pubeurope.com/tags/UK" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#UK</a> <a href="https://pubeurope.com/tags/UnitedKingdom" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#UnitedKingdom</a>

CITO GreenhouseUnraveling the Secrets of Brain Chemistry: The Dance of Serotonin and Beyond!<a href="https://mastodon.social/tags/BrainChemistry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BrainChemistry</a> <a href="https://mastodon.social/tags/Serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Serotonin</a> <a href="https://mastodon.social/tags/MentalHealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MentalHealth</a> <a href="https://mastodon.social/tags/Neuroimaging" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neuroimaging</a> <a href="https://mastodon.social/tags/GABA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GABA</a> <a href="https://mastodon.social/tags/BioactivePeptides" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BioactivePeptides</a> <a href="https://mastodon.social/tags/Genetics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Genetics</a> <a href="https://mastodon.social/tags/WellBeing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#WellBeing</a> <a href="https://mastodon.social/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neuroscience</a> <a href="https://mastodon.social/tags/MoodBoost" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MoodBoost</a> <a href="https://mastodon.social/tags/ScienceExplained" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ScienceExplained</a> <a href="https://mastodon.social/tags/SerotoninTransporter" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SerotoninTransporter</a> <a href="https://mastodon.social/tags/Mindfulness" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Mindfulness</a> <a href="https://mastodon.social/tags/AnxietyRelief" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#AnxietyRelief</a> <a href="https://mastodon.social/tags/HealthAndWellness" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#HealthAndWellness</a><a href="https://youtube.com/shorts/lnLLsplDNQE?feature=share" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://youtube.com/shorts/lnLLsplDNQE?feature=share</a>

CITO GreenhouseUnlocking the Secrets of Our Brains: The Neurobiology Behind Every Thought and Emotion<a href="https://mastodon.social/tags/Neurobiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neurobiology</a> <a href="https://mastodon.social/tags/BrainHealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BrainHealth</a> <a href="https://mastodon.social/tags/BDNF" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BDNF</a> <a href="https://mastodon.social/tags/Dopamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Dopamine</a> <a href="https://mastodon.social/tags/Serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Serotonin</a> <a href="https://mastodon.social/tags/Neuroplasticity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neuroplasticity</a> <a href="https://mastodon.social/tags/Neurogenesis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neurogenesis</a> <a href="https://mastodon.social/tags/BrainFacts" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BrainFacts</a> <a href="https://mastodon.social/tags/MentalWellness" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MentalWellness</a> <a href="https://mastodon.social/tags/BrainScience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BrainScience</a> <a href="https://mastodon.social/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neuroscience</a> <a href="https://mastodon.social/tags/Mindfulness" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Mindfulness</a> <a href="https://mastodon.social/tags/CognitiveHealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CognitiveHealth</a> <a href="https://mastodon.social/tags/NeuroscienceEducation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#NeuroscienceEducation</a> <a href="https://mastodon.social/tags/BrainBoosters" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BrainBoosters</a> <a href="https://mastodon.social/tags/HealthyMind" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#HealthyMind</a><a href="https://youtube.com/shorts/WOLJVwCF3RI?feature=share" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://youtube.com/shorts/WOLJVwCF3RI?feature=share</a>

CITO GreenhouseWhimsical Wonders of Neurobiology: A Journey Through Our Brain's Symphony<a href="https://mastodon.social/tags/Neurobiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neurobiology</a> <a href="https://mastodon.social/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neuroscience</a> <a href="https://mastodon.social/tags/BrainHealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BrainHealth</a> <a href="https://mastodon.social/tags/GABA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GABA</a> <a href="https://mastodon.social/tags/Neurotransmitters" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neurotransmitters</a> <a href="https://mastodon.social/tags/MentalHealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MentalHealth</a> <a href="https://mastodon.social/tags/SSRI" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SSRI</a> <a href="https://mastodon.social/tags/Dopamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Dopamine</a> <a href="https://mastodon.social/tags/Serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Serotonin</a> <a href="https://mastodon.social/tags/Neuroimaging" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neuroimaging</a> <a href="https://mastodon.social/tags/EntericNervousSystem" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#EntericNervousSystem</a> <a href="https://mastodon.social/tags/PsychotropicAgents" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PsychotropicAgents</a> <a href="https://mastodon.social/tags/BrainFunction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BrainFunction</a> <a href="https://mastodon.social/tags/WhimsicalScience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#WhimsicalScience</a> <a href="https://mastodon.social/tags/EmotionalHealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#EmotionalHealth</a> <a href="https://mastodon.social/tags/CognitiveScience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CognitiveScience</a><a href="https://youtube.com/shorts/5_sU6CscCnA?feature=share" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://youtube.com/shorts/5_sU6CscCnA?feature=share</a>

CITO GreenhouseUnlocking the Secrets of Brain Science: Moods, Rhythms, and Neurochemistry<a href="https://mastodon.social/tags/BrainScience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BrainScience</a> <a href="https://mastodon.social/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neuroscience</a> <a href="https://mastodon.social/tags/MoodManagement" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MoodManagement</a> <a href="https://mastodon.social/tags/Serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Serotonin</a> <a href="https://mastodon.social/tags/CircadianRhythms" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CircadianRhythms</a> <a href="https://mastodon.social/tags/NeuroEndocrine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#NeuroEndocrine</a> <a href="https://mastodon.social/tags/MentalHealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MentalHealth</a> <a href="https://mastodon.social/tags/NeuroImmune" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#NeuroImmune</a> <a href="https://mastodon.social/tags/GoodVibes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GoodVibes</a> <a href="https://mastodon.social/tags/BrainHealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#BrainHealth</a> <a href="https://mastodon.social/tags/Psychology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Psychology</a> <a href="https://mastodon.social/tags/MoodTheory" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MoodTheory</a> <a href="https://mastodon.social/tags/ScienceExplained" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ScienceExplained</a> <a href="https://mastodon.social/tags/WellnessJourney" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#WellnessJourney</a><a href="https://youtube.com/shorts/FrbZErc-sCs?feature=share" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://youtube.com/shorts/FrbZErc-sCs?feature=share</a>

earthlingChemically Imbalanced: The Making and Unmaking of the Serotonin Myth by Joanna Moncrieff, 2025For years, we've been led to believe that depression is caused by a chemical imbalance in the brain and antidepressants are the solution. But what if this widely accepted belief has been built on unreliable truths?<a href="https://a.gup.pe/u/bookstodon" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@bookstodon</a> <a href="https://mastodon.social/tags/books" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#books</a> <a href="https://mastodon.social/tags/nonfiction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nonfiction</a> <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://mastodon.social/tags/serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#serotonin</a>

Cochrane DeutschlandDas prämenstruelle Syndrom (<a href="https://wisskomm.social/tags/PMS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PMS</a>) umfasst Beeinträchtigungen des körperlichen, psychischen und sozialen Wohlbefindens von Frauen in den Tagen vor der <a href="https://wisskomm.social/tags/Menstruation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Menstruation</a>, die mit dem Einsetzen der Menstruation nachlassen. Ob selektive <a href="https://wisskomm.social/tags/Serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Serotonin</a>-Wiederaufnahmehemmer im Vergleich zu Placebo bei Frauen mit PMS die selbst eingeschätzten prämenstruellen Symptome verbessern, untersucht ein <a href="https://wisskomm.social/tags/CochraneReview" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CochraneReview</a>: <a href="https://buff.ly/3YLBo1f" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://buff.ly/3YLBo1f</a>

SleepyCattenHey folks 👋For those who don't already know, we're currently signed off work due to depression, anxiety, and burnout.Our employer is supportive, but there are multiple, fundamental, ongoing issues with the organisation that no amount of individual support can resolve. We cannot go into more detail.During the last 2 and a bit weeks, we've done a mixture of resting and doing tasks we've been meaning to do for ages, but neither had the time nor spoons to do.We're still on 200 mg <a href="https://en.wikipedia.org/wiki/Sertraline" rel="nofollow noopener noreferrer" target="_blank">sertraline</a> (an <a href="https://en.wikipedia.org/wiki/Selective_serotonin_reuptake_inhibitor" rel="nofollow noopener noreferrer" target="_blank">SSRI</a>) daily, but we've made the switch from taking 150 mg <a href="https://en.wikipedia.org/wiki/Bupropion" rel="nofollow noopener noreferrer" target="_blank">bupropion</a> (an <a href="https://en.wikipedia.org/wiki/Norepinephrine%E2%80%93dopamine_reuptake_inhibitor" rel="nofollow noopener noreferrer" target="_blank">NDRI</a>) daily alongside to 40 mg <a href="https://en.wikipedia.org/wiki/Atomoxetine" rel="nofollow noopener noreferrer" target="_blank">atomoxetine</a> (an <a href="https://en.wikipedia.org/wiki/Selective_norepinephrine_reuptake_inhibitor" rel="nofollow noopener noreferrer" target="_blank">sNRI</a>, not an <a href="https://en.wikipedia.org/wiki/Serotonin%E2%80%93norepinephrine_reuptake_inhibitor" rel="nofollow noopener noreferrer" target="_blank">SNRI</a>) daily alongside. We're slowly titrating up to the recommend 80 mg dose. As we came off the bupropion steadily, we definitely felt it (i.e., mood; executive function; energy etc.), but the effects are levelling off as our atomoxetine dose steadily increases.The bupropion had helped us for a while, both with our mental health and some ADHD struggles, but could only do so much. As such, we decided to make the unorthodox switch to atomoxetine.Bupropion is an atypical NDRI and antidepressant: it boosts noradrenaline and dopamine (to a lesser extent). However, it's only prescribed off licence for ADHD, as it's not been shown to be effective. Atomoxetine, conversely, is mainly used to treat ADHD in people who do not respond well to stimulants, such as <a href="https://en.wikipedia.org/wiki/Methylphenidate" rel="nofollow noopener noreferrer" target="_blank">methylphenidate</a>. It directly boosts noradrenaline and indirectly boosts dopamine in the prefrontal cortex by a decent amount.Since we do not tolerate any stimulants well (even caffeine), atomoxetine is our best bet in terms of an ADHD med that also helps with our mental health.Unlike bupropion, it doesn't have any major interactions with sertraline (only moderate), and we can take 40 mg <a href="https://en.wikipedia.org/wiki/Propranolol" rel="nofollow noopener noreferrer" target="_blank">propranolol</a> tablets alongside to help keep our anxiety under control, rather than turning straight to 10 mg <a href="https://en.wikipedia.org/wiki/Diazepam" rel="nofollow noopener noreferrer" target="_blank">diazepam</a> tablets. So far, we're doing well with the switch, both physically and mentally, but it'll be a while before we know for sure whether this the ideal medication combination.We are still very much in low power recovery mode, so don't expect anything much or consistent from us.A last note to sign this off: from the above listed drugs, the only one we can currently get via the NHS is sertraline. We may be able to get atomoxetine through the NHS in the future, but that's dependent on us ever actually getting a formal ADHD diagnosis 😮‍💨 The waiting lists are rather long... even when using the <a href="https://www.nhs.uk/mental-health/social-care-and-your-rights/how-to-access-mental-health-services/#choice" rel="nofollow noopener noreferrer" target="_blank">Right To Choose</a> a mental health service provider.Apologies for any typos.<a href="https://cultofshiv.wtf/tags/MentalHealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MentalHealth</a> <a href="https://cultofshiv.wtf/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://cultofshiv.wtf/tags/anxiety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#anxiety</a> <a href="https://cultofshiv.wtf/tags/burnout" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#burnout</a> <a href="https://cultofshiv.wtf/tags/neurodivergent" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neurodivergent</a> <a href="https://cultofshiv.wtf/tags/ADHD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ADHD</a> <a href="https://cultofshiv.wtf/tags/AuDHD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#AuDHD</a> <a href="https://cultofshiv.wtf/tags/NHS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#NHS</a> <a href="https://cultofshiv.wtf/tags/NHSEngland" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#NHSEngland</a> <a href="https://cultofshiv.wtf/tags/sertraline" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#sertraline</a> <a href="https://cultofshiv.wtf/tags/SSRI" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SSRI</a> <a href="https://cultofshiv.wtf/tags/bupropion" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bupropion</a> <a href="https://cultofshiv.wtf/tags/NDRI" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#NDRI</a> <a href="https://cultofshiv.wtf/tags/atomoxetine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#atomoxetine</a> <a href="https://cultofshiv.wtf/tags/sNRI" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#sNRI</a> <a href="https://cultofshiv.wtf/tags/serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#serotonin</a> <a href="https://cultofshiv.wtf/tags/noradrenaline" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#noradrenaline</a> <a href="https://cultofshiv.wtf/tags/dopamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dopamine</a> <a href="https://cultofshiv.wtf/tags/RightToChoose" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#RightToChoose</a> <a href="https://cultofshiv.wtf/tags/propranolol" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#propranolol</a> <a href="https://cultofshiv.wtf/tags/diazepam" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#diazepam</a> <a href="https://cultofshiv.wtf/tags/stimulants" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#stimulants</a> <a href="https://cultofshiv.wtf/tags/methylphenidate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#methylphenidate</a>

Moritz NegwerNew <a href="https://mstdn.science/tags/tissueclearing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#tissueclearing</a> <a href="https://mstdn.science/tags/preprint" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#preprint</a> uses a custom mouse behaviour + deep-learning c-Fos analysis pipeline to compare several different Serotonin receptor agonists / antagonists in mice. Concerted modulation of spontaneous behavior and time-integrated whole-brain neuronal activity by serotonin receptors Friedmann et al., preprint at biorxiv 2024 <a href="https://doi.org/10.1101/2024.08.02.606282" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://doi.org/10.1101/2024.08.02.606282</a> <a href="https://mstdn.science/tags/lightsheet" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#lightsheet</a> <a href="https://mstdn.science/tags/microscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#microscopy</a> <a href="https://mstdn.science/tags/serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#serotonin</a> <a href="https://mstdn.science/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a> <a href="https://mstdn.science/tags/preprint" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#preprint</a> <a href="https://mstdn.science/tags/brainmapping" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#brainmapping</a>

Benjamin Carr, Ph.D. 👨🏻‍💻🧬Chemical tweaks to a <a href="https://hachyderm.io/tags/toad" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#toad</a> <a href="https://hachyderm.io/tags/hallucinogen" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#hallucinogen</a> turns it into a potential <a href="https://hachyderm.io/tags/drug" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#drug</a> Targets a different <a href="https://hachyderm.io/tags/serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#serotonin</a> receptor from other popular <a href="https://hachyderm.io/tags/hallucinogens" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#hallucinogens</a>. The Colorado River toad (Incilius alvarius), also known as the Sonoran Desert toad, secretes a <a href="https://hachyderm.io/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> compound that likes to bind to a different <a href="https://hachyderm.io/tags/serotoninreceptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#serotoninreceptor</a> subtype called <a href="https://hachyderm.io/tags/5HT1A" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#5HT1A</a>. And that difference may be the key to developing an entirely distinct class of <a href="https://hachyderm.io/tags/antidepressants" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#antidepressants</a>. <a href="https://arstechnica.com/science/2024/05/variant-of-a-toad-based-psychedelic-can-act-as-an-antidepressant/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://arstechnica.com/science/2024/05/variant-of-a-toad-based-psychedelic-can-act-as-an-antidepressant/</a>

Spektrum (inoffiziell)Die meisten Medikamente gegen psychische Störungen greifen in den Hirnstoffwechsel ein. Was das langfristig mit unserem Denkorgan anstellt, ist bei vielen dieser Arzneien unklar.<a href="https://anonsys.net/search?tag=Psychopharmaka" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Psychopharmaka</a> <a href="https://anonsys.net/search?tag=Medikamente" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Medikamente</a> <a href="https://anonsys.net/search?tag=Antidepressiva" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Antidepressiva</a> <a href="https://anonsys.net/search?tag=Antipsychotika" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Antipsychotika</a> <a href="https://anonsys.net/search?tag=Neuroleptika" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neuroleptika</a> <a href="https://anonsys.net/search?tag=Psyche" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Psyche</a> <a href="https://anonsys.net/search?tag=PsychischeSt%C3%B6rung" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PsychischeStörung</a> <a href="https://anonsys.net/search?tag=Gehirn" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Gehirn</a> <a href="https://anonsys.net/search?tag=Plastizit%C3%A4t" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Plastizität</a> <a href="https://anonsys.net/search?tag=Hirnstoffwechsel" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Hirnstoffwechsel</a> <a href="https://anonsys.net/search?tag=Botenstoffe" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Botenstoffe</a> <a href="https://anonsys.net/search?tag=Neurotransmitter" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neurotransmitter</a> <a href="https://anonsys.net/search?tag=Dopamin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Dopamin</a> <a href="https://anonsys.net/search?tag=Serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Serotonin</a> <a href="https://anonsys.net/search?tag=Depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Depression</a> <a href="https://anonsys.net/search?tag=Schizophrenie" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Schizophrenie</a> <a href="https://anonsys.net/search?tag=Psychose" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Psychose</a> <a href="https://anonsys.net/search?tag=ADHS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ADHS</a> <a href="https://anonsys.net/search?tag=Ritalin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Ritalin</a> #<a href="https://anonsys.net/search?tag=" rel="nofollow noopener noreferrer" target="_blank">anonsys.net/search?tag=</a> <a href="https://anonsys.net/search?tag=Medizin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Medizin</a> <a href="https://www.spektrum.de/news/langzeittherapie-wie-psychopharmaka-das-gehirn-veraendern/2206381" rel="nofollow noopener noreferrer" target="_blank">Wie Psychopharmaka das Gehirn verändern</a>

🌪 MikeMathia.com 📡<a href="https://ioc.exchange/tags/Serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Serotonin</a>

★discrust★<a href="https://chaos.social/tags/serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#serotonin</a> <a href="https://chaos.social/tags/graphic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#graphic</a>

LaborjournalEin Überschuss des "Glückshormons" <a href="https://mstdn.science/tags/Serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Serotonin</a> im Körper macht krank. Michael Bader & Co. spürten Inhibitoren eines Enzyms der Serotonin-Synthese auf – und gründeten auf dieser Basis Trypto Therapeutics. Larissa Tetsch porträtiert das Berliner <a href="https://mstdn.science/tags/Biotech" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Biotech</a>-<a href="https://mstdn.science/tags/Startup" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Startup</a>: <a href="https://laborjournal.de/editorials/2927.php" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://laborjournal.de/editorials/2927.php</a>

das_menschyBy <a href="https://c.im/@RIDDLES" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@RIDDLES</a>: Happiness Chemicals and How to Hack Them <a href="https://toot.bike/tags/Dopamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Dopamine</a> <a href="https://toot.bike/tags/Oxytocin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Oxytocin</a> <a href="https://toot.bike/tags/Endorphin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Endorphin</a> <a href="https://toot.bike/tags/Serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Serotonin</a>

Moritz NegwerHistone Serotonylation is one of the crazier epigenetic modifications - <a href="https://mstdn.science/tags/Serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Serotonin</a>, the neurotransmitter, is shuttled into the nucleus and coupled to specific glutamine residues on the histone tails. This happens not only in the brain, but apparently also in the placenta, this new paper shows: Serotonin transporter-dependent histone serotonylation in placenta contributes to the neurodevelopmental transcriptome Chan et al., J Mol B 2024 <a href="https://doi.org/10.1016/j.jmb.2024.168454" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://doi.org/10.1016/j.jmb.2024.168454</a><a href="https://mstdn.science/tags/epigenetics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epigenetics</a> <a href="https://mstdn.science/tags/histone" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#histone</a>

PLOS Biology<a href="https://fediscience.org/tags/Serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Serotonin</a> deficiency underlies <a href="https://fediscience.org/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> & disorders of motivation. Behavioral analysis & pharm manipulation in monkeys reveals distinct contributions of <a href="https://fediscience.org/tags/SerotoninReceptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SerotoninReceptor</a> subtypes to reduced <a href="https://fediscience.org/tags/motivation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#motivation</a> in terms of cost-benefit trade-offs <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PLOSBiology</a> <a href="https://plos.io/48kB11t" rel="nofollow noopener noreferrer" target="_blank">https://plos.io/48kB11t</a>

-/mondsternWas ist eigentlich dieses <a href="https://mastodon.green/tags/serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#serotonin</a>

Benjamin Carr, Ph.D. 👨🏻‍💻🧬The <a href="https://hachyderm.io/tags/Evolution" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Evolution</a> and Origins of <a href="https://hachyderm.io/tags/Psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Psychedelics</a> Quite simply, many baroque <a href="https://hachyderm.io/tags/chemicals" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#chemicals</a> we use and abuse appeared on the planet because they enhance the survival odds of the organisms that make them or absorb them. Psychedelics are chemicals that bind to and activate <a href="https://hachyderm.io/tags/serotonin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#serotonin</a> receptors in our brains. Just as natural psychedelics evolved independently in many organisms, so, too, did their cultural use over and over by Indigenous peoples around the world. <a href="https://time.com/6340163/evolutionary-origins-psychedelics-essay/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://time.com/6340163/evolutionary-origins-psychedelics-essay/</a>

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